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  • Migraine Trigger or Prodromal Symptom: Which Came First — the Chocolate or the Craving?

    Knowledge of the differentiation between the triggers for a potential migraine attack and the prodromal symptoms of an initiated migraine attack reveals strategies that decrease migraine disability. Recognition of migraine triggers allows for a modification of behavior to avoid precipitating an attack. Recognition of common migraine prodromal symptoms creates an early time window when rapid treatment enhances the therapeutic intervention’s efficacy.

  • Infectious Disease Updates

    Is Your Hospital Bed Contaminated? The Surgical Skin Prep Debate Thickens

  • Outpatient CAP Treatment in Adults: Narrower Spectrum Therapy Is Better Tolerated

    Examination of a large database led to the conclusion that treatment of community-acquired pneumonia in outpatients with narrower-spectrum agents (macrolides or doxycycline) was associated with similar clinical outcomes but with a lower incidence of adverse effects when compared to broader-spectrum therapy.

  • Parasites and Poverty in the South

    Parasite contamination of soil remains prevalent in some areas of the southern United States.

  • Aztreonam-Avibactam vs. Meropenem for Serious Gram-Negative Bacterial Infections

    In this multinational, prospective, Phase III, randomized trial, aztreonam-avibactam was found to be a safe and effective option, when compared to meropenem with or without colistin, for treating complicated intra-abdominal infections, hospital-acquired pneumonia, and ventilator-acquired pneumonia caused by gram-negative bacteria.

  • Effectiveness of Nirmatrelvir-Ritonavir in Hospitalized Patients with COVID-19

    A study that compared nirmatrelvir-ritonavir, remdesivir, or a combination of both for hospitalized patients with COVID-19 found those who received nirmatrelvir-ritonavir monotherapy had lower mortality, reduced intensive care unit admission, and reduced need for mechanical ventilation.

  • Pink Eye: Do Antibiotics Matter?

    Acute infectious conjunctivitis, commonly referred to as pink eye, is common in children and is caused by bacteria more often than by viruses. Nonetheless, neither the clinical course of uncomplicated cases nor the spread of infection to peers is significantly altered by treatment with topical antibiotics or by exclusion of infected children from daycare and school settings.

  • Colonic Emergencies

    Abdominal pain is one of the most frequent chief complaints an emergency clinician will evaluate. Some of the most frequently encountered colonic emergencies, including large bowel obstruction, acute colonic pseudo-obstruction, diverticulitis, toxic megacolon, scybala, volvulus, hemorrhoids, rectal prolapse, and constipation, will be reviewed in this article.

  • Left Atrial vs. Left Ventricular Parameters for Intervention Decisions

    A one-institution study of serial echocardiograms in patients with moderate to severe or severe aortic regurgitation demonstrated that changes in left atrial size and strain changed over time in a similar fashion regardless of sex and age, and were of incremental prognostic value compared to left ventricular size and function.

  • Screening Relatives of Hypertrophic Cardiomyopathy Patients

    A retrospective cohort study of the first-degree relatives of patients with hypertrophic cardiomyopathy (HCM) seen in screening clinics in Denmark has shown that the diagnostic yield of the first visit is 26% and subsequent visits add 4%. The best predictor of the development of HCM in relatives of families with negative genetic findings was maximal left ventricular wall thickness of ≥ 10 mm.